We call OCT with speeds of more than 1.000.000 axial scans per second MHz-OCT. These unprecedented speeds require not only an extremely fast swept laser, such as our FDML products, but also rely on perfect synchronization, powerful data processing and other system technologies.
Optores is a spin-off from Ludwig-Maximilians-University in Munich, Germany, where pioneering work on MHz-OCT has been performed, including the following publications:
- Wieser, W., Biedermann, B. R., Klein, T., Eigenwillig, C. M., und Huber, R.: Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second. Optics Express, vol. 18, no. 14, pp. 14685-704, Jul 2010 doi:10.1364/OE.18.014685
- Klein, T., Wieser, W., Eigenwillig, C. M., Biedermann, B. R., und Huber, R.: Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser. Optics Express, vol. 19, no. 4, pp. 3044-62, Feb 2011 doi:10.1364/OE.19.003044
- Blatter, C., Klein, T., Grajciar, B., Schmoll, T., Wieser, W., Andre, R., Huber, R., und Leitgeb, R. A.: Ultrahigh-speed non-invasive widefield angiography. Journal of Biomedical Optics, vol. 17, no. 7, pp. 070505 1-3, Jul, 2012 doi:10.1117/1.JBO.17.7.070505
- Wieser, W., Klein, T., Adler, D. C., Trepanier, F., Eigenwillig, C. M., Karpf, S., Schmitt, J. M., und Huber, R.: Extended coherence length megahertz FDML and its application for anterior segment imaging. Biomedical Optics Express, vol. 3, no. 10, pp. 2647-57, Oct 2012 doi:10.1364/BOE.3.002647
- Klein, T., Wieser, W., Reznicek, L., Neubauer, A., Kampik, A., und Huber, R.: Multi-MHz retinal OCT. Biomedical Optics Express, vol. 4, no. 10, pp. 1890-908, Jan 2013 doi:10.1364/BOE.4.001890
- Klein, T., Andre, R., Wieser, W., Pfeiffer, T., und Huber, R.: Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT. Biomedical Optics Express, vol. 4, no. 4, pp. 619-34, Apr 2013 doi:10.1364/BOE.4.000619
- Wieser, W., Draxinger, W., Klein, T., Karpf, S., Pfeiffer, T., und Huber, R.: High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s. Biomedical Optics Express, vol. 5, no. 9, pp. 2963-77, Sep, 2014 doi:10.1364/BOE.5.002963
- Kolb, J. P., Klein, T., Kufner, C. L., Wieser, W., Neubauer, A. S., und Huber, R.: Ultra-widefield retinal MHz-OCT imaging with up to 100 degrees viewing angle. Biomedical Optics Express, vol. 6, no. 5, pp. 1534-1552, May 2015 doi:10.1364/BOE.6.001534